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Bavituximab (TAB-175)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Phosphatidylserine Therapeutic Antibody TAB-175 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to phosphatidylserine. Bavituximab is a chimeric monoclonal antibody designed for the treatment of cancers and viral infections.
  • Target
  • phosphatidylserine
  • Type
  • IgG1 - kappa
  • Immunogen
  • Liposomes containing 70% phosphatidylserine and 30% phosphatidylglycerol.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • CAS
  • 648904-28-3
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1,anti-(phosphatidylserine) (human-mouse monoclonal ch3G4 heavy chain), disulfidewith human-mouse monoclonal ch3G4 k-chain, dimer
  • Predicted N terminal
  • H chain: EVQLQQS; L chain: DIQMTQS
  • Molecular Weight
  • 145300
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Introduction
  • Chimeric monoclonal antibody designed for the treatment of cancers and viral infections.
  • Antigen Description
  • Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid component, usually kept on the inner-leaflet (the cytosolic side) of cell membranes by an enzyme called flippase. When a cell undergoes apoptosis, phosphatidylserine is no longer restricted to the cytosolic part of the membrane, but becomes exposed on the surface of the cell.
  • Keywords
  • Phosphatidylserine; PS; Ptd-L-Ser

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