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Narnatumab (TAB-184)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human RON Therapeutic Antibody TAB-184 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to RON. Narnatumab is a human monoclonal antibody designed for the treatment of cancer.
  • Target
  • RON
  • Type
  • IgG1 - kappa
  • Immunogen
  • RE7 cells and MDCK cells overexpressing the human RON receptor in complete Freund`s adjuvant
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • CAS
  • 1188275-92-4
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human macrophage-stimulating protein receptor); human monoclonal IMC-RON8 γ1 heavy chain (225-214")-disulfide with human monoclonal IMC-RON8 kappa light chain, dimer (231-231"":234-234"")-bisdisulfide
  • Predicted N terminal
  • H chain: EVQLVES; L chain: EIVLTQS
  • Molecular Weight
  • 145900
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.
  • Function
  • ATP binding; enzyme binding; macrophage colony-stimulating factor receptor activity; nucleotide binding; protein binding; receptor activity;
  • Synonyms
  • MST1R; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); PTK8, PTK8 protein tyrosine kinase 8 , RON; macrophage-stimulating protein receptor; CD136; CDw136; p185-Ron; MSP receptor; RON variant E2E3; MST1R variant RON30; MST1R variant RON62; soluble RON variant 1; soluble RON variant 2; soluble RON variant 3; soluble RON variant 4; c-met-related tyrosine kinase; PTK8 protein tyrosine kinase 8; RON; PTK8;

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