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Pateclizumab (TAB-071)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human TNF beta therapeutic Antibody TAB-071 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to TNF beta. Pateclizumab is an immunomodulator. It binds to lymphotoxin alpha.
  • Target
  • TNF beta
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
  • CAS
  • 1202526-59-7
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human lymphotoxin alpha) (human-mouse monoclonal MLTA3698A heavy chain), disulfide with human-mouse monoclonal MLTA3698A light chain, dimer
  • Predicted N terminal
  • H Chain: EVQLVES; L Chain: DIQMTQS
  • Molecular Weight
  • 144714
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
  • Function
  • cytokine activity; receptor binding; tumor necrosis factor receptor binding;
  • Synonyms
  • LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;

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