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Recombinant monoclonal antibody to TNF beta. Pateclizumab is an immunomodulator. It binds to lymphotoxin alpha.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
Tested positive against native human antigen.
Immunoglobulin G1, anti-(human lymphotoxin alpha) (human-mouse monoclonal MLTA3698A heavy chain), disulfide with human-mouse monoclonal MLTA3698A light chain, dimer
Predicted N terminal
H Chain: EVQLVES; L Chain: DIQMTQS
>95.0% as determined by analysis by SDS-PAGE.
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.