mapatumumab (TAB-H48)

Anti-Human TNFRSF10A Recombinant Antibody TAB-H48 1mg Please Inquiry


  • Product Overview
  • Recombinant human antibody to Human TNFRSF10A. Mapatumumab (HGS-ETR1) is an experimental human monoclonal antibody for the treatment of cancer.
  • Type
  • IgG1
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, IHC and most other immunological methods.
  • CAS
  • 658052-09-6
  • Specific Activity
  • TNFRSF10A(tumor necrosis factor receptor (TNFR) superfamily member 10A, death receptor 4, DR4, TNF-related apoptosis-inducing ligand receptor 1, TRAILR1, TRAIL-R1, TR-1, CD261) agonistic antibody [Homo sapiens]
  • Protein Construction
  • immunoglobulin G1, anti-(human cytokine receptor DR4 (death receptor 4))(human monoclonal TRM-1 heavy chain), disulfide with humanmonoclonal TRM-1 λ-chain, dimer
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.


  • Antigen Description
  • Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002
  • Function
  • TRAIL binding; death receptor activity; protein binding; receptor activity; transcription factor binding;
  • Synonyms
  • TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; tumor necrosis factor receptor superfamily member 10A; Apo2; CD261; DR4; TRAILR 1; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2; APO2; TRAILR1; TRAILR-1; MGC9365;

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