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Enavatuzumab (TAB-178)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human TWEAK receptor Therapeutic Antibody TAB-178 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to TWEAK receptor. Drozitumab is a human monoclonal antibody designed for the treatment of cancers.
  • Target
  • TWEAK receptor
  • Type
  • IgG1 - kappa
  • Immunogen
  • Human Fn14 transfected P815.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
  • CAS
  • 912628-39-8
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1-lambda, anti-[Homo sapiens TNFRSF10B (tumor necrosis factor receptor superfamily member 10B, DR5, death receptor 5, TRAIL-R2, TNF-related apoptosis-inducing ligand receptor 2, TR-2, CD262)], Homo sapiens monoclonal antibody
  • Predicted N terminal
  • H chain: EVQLVES; L chain: DIQMTQS
  • Molecular Weight
  • 143100
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
  • Function
  • cytokine activity; cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding;
  • Synonyms
  • TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; MGC20669; MGC129581;

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