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Pritumumab (TAB-214)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Vimentin Therapeutic Antibody TAB-214 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to Vimentin. Pritumumab is a human monoclonal antibody used in the treatment of brain cancer.
  • Target
  • Vimentin
  • Type
  • IgG1
  • Immunogen
  • synthetic acetylated peptide of Human Vimentin.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
  • CAS
  • 499212-74-7
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G, anti-(human vimentin) (human monoclonal CLN G11 g1-chain), disulfide with human monoclonal CLN G11 k-chain, dimer
  • Molecular Weight
  • 150000
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
  • Function
  • identical protein binding; protein C-terminus binding; protein binding; structural constituent of cytoskeleton;
  • Synonyms
  • VIM; vimentin; FLJ36605;

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