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Recombinant human monoclonal antibody expressed in CHO binding to human IGF2. Dusigitumab is a human monoclonal antibody designed for the treatment of cancer.
The details of the immunogen for this antibody are not available.
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, IHC and most other immunological methods.
Predicted N terminal
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Dusigitumab is a human monoclonal antibody designed for the treatment of cancer.
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.