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ligelizumab (TAB-755)

DESCRIPTION CATALOG # SIZE PRICE
Anti-IGHE Therapeutic Antibody TAB-755 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized antibody expressed in CHO binding to human IGHE. Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
  • Target
  • IGHE
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
  • CAS
  • 1322627-61-1
  • Predicted N terminal
  • QVQLVQSG
  • Molecular Weight
  • 46.96 kDa
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Introduction
  • Ligelizumab is a humanized monoclonal antibody that binds to IGHE.
  • Antigen Description
  • The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
  • Synonyms
  • IGHE; Immunoglobulin heavy constant epsilon;

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