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Recombinant humanized antibody expressed in CHO binding to human IGHE. Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
Predicted N terminal
Purity >95% by SDS-PAGE.
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Ligelizumab is a humanized monoclonal antibody that binds to IGHE.
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.