diridavumab(CR6261)

Cat

TAB-735

Product Overview

Recombinant human monoclonal antibody expressed in CHO binding to Influenza A hemagglutinin. CR6261 is a monoclonal antibody that binds to a broad range of the influenza virus. Based upon the conservation of the amino acid sequence on this part of hemagglutinin, CR6261 is predicted to neutralize roughly 50% of all flu viruses.

Target

Influenza A hemagglutinin

Type

IgG1 - lambda

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

influenza virus

Expression Host

CHO

Applications

Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, IHC and most other immunological methods.

CAS

1393659-46-5

Predicted N terminal

EVQLVESG

Molecular Weight

Approximately 150 kDa

Purity

>95.0% as determined by analysis by RP-HPLC.

Size

1mg

Storage

At -20°C for one year.

Introduction

Influenza A (H1N1) virus is a subtype of influenza A virus and was the most common cause of human influenza (flu) in 2009. Some strains of H1N1 are endemic in humans and cause a small fraction of all influenza-like illness and a small fraction of all seasonal influenza. H1N1 strains caused a few percent of all human flu infections in 2004–2005Other strains of H1N1 are endemic in pigs (swine influenza) and in birds (avian influenza).

Antigen Description

Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes.

Keywords

Influenza A Hemagglutinin; Influenza A; H1N1; Group V ((-)ssRNA); Orthomyxoviridae; S-OIV A Hemagglutinin; Swine flu H1

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