Close

lirilumab (TAB-757)

DESCRIPTION CATALOG # SIZE PRICE
Anti-KIRD2 subgroup Recombinant Antibody TAB-757 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant human monoclonal antibody expressed in CHO binding to human KIRD2 subgroup. Lirilumab is a human monoclonal antibody designed for the treatment of cancer.
  • Target
  • KIRD2 subgroup
  • Type
  • IgG4 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
  • CAS
  • 1000676-41-4
  • Predicted N terminal
  • QVQLVQSG
  • Molecular Weight
  • 145.2 kDa
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Introduction
  • KIRs are human natural killer (NK) cell receptors for MHC class I molecules. Most inhibit the activity of NK cells thus preventing cell lysis. Two main families of receptors for HLA class I have been discovered on human NK cells: Killer cell Immunoglobulin-like receptors (KIR) and CD94/NKG2 heterodimers. The KIR receptors are an extremely diverse family of receptors. In addition to receptors for HLA, NK cells also express pattern recognition receptors e.g. TLRs and Nod proteins.
  • Antigen Description
  • Human KIRD2 subgroup (killer cell Immunoglobulin-like Receptor subgroup, including KIR2DL1 (nkat1/CD158A), KIR2DL2 (nkat6/CD158B1), KIR2DL3 (nkat2/CD158B2), KIR2DS1 (CD158H) and KIR2DS2 -nkat5/CD158J-)
  • Keywords
  • Killer-cell immunoglobulin-like receptors; KIRs; KIR2DL1/2/3

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

Online Inquiry

Verification code
Click image to refresh the verification code.

CONTACT US

USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us