Close

Indium (111In) imciromab (TAB-708)

DESCRIPTION CATALOG # SIZE PRICE
Anti-cardiac myosin Recombinant Antibody (Myoscint) TAB-708 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant mouse monoclonal antibody Fab fragment expressed in CHO binding to human cardiac myosin. Indium (111In) imciromab is a mouse monoclonal antibody and was used for cardiac imaging, but withdrawn in 1993.
  • Target
  • cardiac myosin
  • Type
  • Mouse Fab IgG2a - kappa - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • Murine ascites, pepsin digestion
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
  • CAS
  • 126132-83-0
  • Trade name
  • Myoscint
  • Molecular Weight
  • Approximately 47 kDa
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Introduction
  • Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. Th
  • Antigen Description
  • Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

Online Inquiry

Verification code
Click image to refresh the verification code.

CONTACT US

USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us