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efungumab (TAB-704)

DESCRIPTION CATALOG # SIZE PRICE
Anti-fungal Hsp90 Therapeutic Antibody (MYCOGRAB) TAB-704 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant human monoclonal antibody scFv fragment expressed in E. Coli binding to heat shock protein 90 homolog [Candida albicans]. Efungumab is a drug intended to treat invasive Candida infection in combination with amphotericin B.
  • Target
  • heat shock protein 90 homolog [Candida albicans]
  • Type
  • scFv - heavy - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • fungal
  • Expression Host
  • E. Coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
  • CAS
  • 762260-74-2
  • Trade name
  • mycograb
  • Predicted N terminal
  • MAEVQLVE
  • Molecular Weight
  • 27.2 kDa
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Introduction
  • Efungumab is a single-chain variable fragment of a human monoclonal antibody, intended to treat invasive Candida infection in combination with amphotericin B.
  • Antigen Description
  • C. albicans is commensal and a constituent of the normal gut flora comprising microorganisms that live in the human mouth and gastrointestinal tract. C. albicans lives in 80% of the human population without causing harmful effects, although overgrowth of the fungus results in candidiasis (candidosis).
  • Keywords
  • fungal Hsp90

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