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Recombinant human monoclonal antibody scFv fragment expressed in E. Coli binding to heat shock protein 90 homolog [Candida albicans]. Efungumab is a drug intended to treat invasive Candida infection in combination with amphotericin B.
heat shock protein 90 homolog [Candida albicans]
scFv - heavy - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
Predicted N terminal
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Efungumab is a single-chain variable fragment of a human monoclonal antibody, intended to treat invasive Candida infection in combination with amphotericin B.
C. albicans is commensal and a constituent of the normal gut flora comprising microorganisms that live in the human mouth and gastrointestinal tract. C. albicans lives in 80% of the human population without causing harmful effects, although overgrowth of the fungus results in candidiasis (candidosis).