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Anti-B. anthracis PA Antibody Fab (MOM-18224-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-B. anthracis PA Antibody Fab Fragment MOM-18224-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human Antibody Fab Fragment binds selectively to Bacillus anthracis, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • Bacillus anthracis
  • Type
  • Fab Fragment based on Human IgG1 - lambda
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • B. anthracis
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Introduction
  • This is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax.
  • Antigen Description
  • Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments.
  • Keywords
  • anthrax PA; Anthrax Protective Antigen; Anthrax toxins translocating protein; Bacillus anthracis Protective Antigen; PA 83; PA; PA83; Pag; PagA; Protective antigen

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