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Recombinant Humanized (from mouse) Antibody Fab Fragment is bind to Human CCR4, expressed in Chinese Hamster Ovary cells(CHO)
Fab Fragment based on Humanized (from mouse) IgG1 - kappa
KLH conjugate CCR4 partial peptide
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIVMTQS
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.