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Recombinant Mouse Antibody Fab Fragment is against Human CD22, expressed in Chinese Hamster Ovary cells(CHO)
Fab Fragment based on Mouse Fab' - G2a - kappa
A combination of recombinant human CD22 extracellular 25 domain and CHO ceIls engineered to express full-length human CD22 on the ceIl surface
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Immunoglobulin G2a, anti-(human CD22 (antigen))Fab fragment (mouse monoclonal IMMU-LL2 g2a-chain), disulfide with mousemonoclonal IMMU-LL2 light chain
Predicted N terminal
H chain: EVQLVQS; L Chain: EIVLTQS
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling.