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Recombinant Anti-CEA MAb Fab (MOM-H03-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CEA Antibody Fab Fragment MOM-H03-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment specifically binds to Human CEA, expressed in E. coli
  • Target
  • CEA
  • Type
  • Mouse Fab-IgG
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Purification
  • Purified by Nickel ion affinity chromatography
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Introduction
  • Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
  • Keywords
  • CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; BGP1; BGPI; antigen CD66; CD66a antigen; CEACAM3; carcinoembryonic antigen-related cell adhesion molecule 3; CEA; CGM1; Carcinoembryonic antigen

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