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Recombinant Mouse Antibody specifically binds to Human CEA, expressed in HEK293
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Purified by protein-A affinity chromatography.
Store at -20°C. Avoid multiple freeze/thaw cycles.
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.