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Recombinant Human Antibody Fab Fragment is directed against Human VEGFR-1, expressed in Chinese Hamster Ovary cells(CHO)
Fab Fragment based on Human IgG1 - kappa
Recombinant human soluble extracellular Flt-1 Ig-like loop 1 to 5 (sFlt-1(D5)).
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Predicted N terminal
H chain: QAQVVES; L Chain: EIVLTQS
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
At -20°C for one year.
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
ATP binding; growth factor binding; nucleotide binding; protein binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity; vascular endothelial growth factor-activated receptor activity;