Anti-GP6 Antibody

Cat

MOM-18373

Product Overview

Recombinant Mouse Antibody is specific to Human GP6, expressed in Chinese Hamster Ovary cells(CHO)

Target

GP6

Type

IgG

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in WB, ELISA, IP, FC, FuncS, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Antigen Description

Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation. GPVI is expressed in megakaryocytes and platelets. Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen. There are three isoforms.

Function

collagen binding; protein binding; receptor activity; transmembrane signaling receptor activity;

Gene ID

51206

Synonyms

GP6; glycoprotein VI (platelet); platelet glycoprotein VI; GPVI; glycoprotein 6; platelet collagen receptor; GPIV; BDPLT11; MGC138168

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