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Anti-ICAM1 Antibody Fab (MOM-18241-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ICAM1 Antibody Fab Fragment MOM-18241-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment binds selectively to Human ICAM-1, expressed in E. coli
  • Target
  • ICAM-1
  • Type
  • Fab Fragment based on Mouse Fab' - G2a
  • Immunogen
  • Tissue / cell preparation (Human). (Burkitt's lymphoma cell line RAJI).
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
  • Function
  • cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;
  • Synonyms
  • ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;

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