Anti-IL6 Antibody Fab

Cat

MOM-18253-F(P)

Product Overview

Recombinant Humanized (from rat) Antibody Fab Fragment is against Human IL-6, expressed in E. coli

Target

IL-6

Type

Fab Fragment based on Humanized (from rat) IgG4 - kappa

Immunogen

Recombinant full length protein (Human).

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Predicted N terminal

H chain: EVQLLES; L Chain: DIQMTQS

Purity

>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Antigen Description

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Function

cytokine activity; cytokine activity; growth factor activity; interleukin-6 receptor binding; contributes_to interleukin-6 receptor binding; interleukin-6 receptor binding;

Gene ID

3569

Synonyms

IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2; HGF; HSF; IL 6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor; IL-6;

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