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Recombinant Humanized (from rat) Antibody Fab Fragment is bind to Human Integrin alpha 4 beta 7, expressed in Chinese Hamster Ovary cells(CHO)
Integrin alpha 4 beta 7
Fab Fragment based on Humanized (from rat) IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
>95.0% as determined by analysis by RP-HPLC.
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer"s patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer"s patches and intestinal lamina propria.
fibronectin binding; protein binding; receptor activity;