Close

Anti-ITGA4 Antibody (MOM-18022)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA4 Antibody MOM-18022 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) Antibody is directed against Human ITGA4, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • ITGA4
  • Type
  • Humanized (from mouse) IgG4
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Protein Construction
  • Immunoglobulin G4, anti-(human integrin R4) (human-mouse monoclonal AN100226 gamma 4-chain), disulfide with human-mouse monoclonal AN100226 light chain, dimer
  • Predicted N terminal
  • H Chain: QVQLVQS; L Chain: DIQMTQS
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4- positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
  • Function
  • fibronectin binding; protein binding; receptor activity;
  • Synonyms
  • ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49D; integrin alpha-4; CD49d; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D, alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor, alpha 4 subunit; IA4; MGC90518;

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

Online Inquiry

Verification code
Click image to refresh the verification code.

CONTACT US

USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us