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Recombinant Anti-ITGA4+ITGB7 MAb Fab (MOM-H75-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA4+ITGB7 Antibody Fab Fragment MOM-H75-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) Antibody Fab Fragment is directed agains Human ITGA4+ITGB7, expressed in HEK293
  • Target
  • ITGA4+ITGB7
  • Type
  • Humanized (from mouse) Fab-IgG1 - kappa
  • Species Reactivity
  • Human
  • Expression Host
  • HEK293
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA and most other immunological methods.
  • Specificity
  • ITGA4_ITGB7(integrin alpha4 (CD49d)_beta7, integrin alpha4_beta7, integrin α4β7, lymphocyte Peyer s patch adhesion molecule 1, LPAM-1) [Homo sapiens]
  • Cellular Localization
  • kappa
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Purification
  • Purified by Nickel ion affinity chromatography
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Introduction
  • Integrins are transmembrane receptors that are the bridges for cell-cell and cell-extracellular matrix (ECM) interactions. When triggered, integrins in turn trigger chemical pathways to the interior (signal transduction), such as the chemical composition and mechanical status of the ECM, which results in a response (activation of transcription) such as regulation of the cell cycle, cell shape, and/or motility; or new receptors being added to the cell membrane
  • Keywords
  • ITGA4; ITGB7; Integrin α4β7; CD49d/β7

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