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Recombinant Chimeric (mouse/human) Antibody is directed against Human Integrin alpha 5 beta 1, expressed in Chinese Hamster Ovary cells(CHO)
Integrin alpha 5 beta 1
Chimeric (mouse/human) IgG4
The details of the immunogen for this antibody are not available.
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
Tested positive against native antigen.
Immunoglobulin G4, anti-(human a5b1 integrin) (human-mouse clone p200-M heavy chain), disulfide with human-mouse clone p200-M k-chain, dimer
Predicted N terminal
H Chain: MAVLGLL; L Chain: MDFQVQV
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
This protein belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha V chain. Alpha chain V undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.