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Recombinant Human Antibody Fab Fragment binds selectively to Human CD51, expressed in Chinese Hamster Ovary cells(CHO)
Fab Fragment based on Human IgG1 - kappa
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Predicted N terminal
H Chain: QVQLVES; L Chain: EIVLTQS
>95.0% as determined by analysis by RP-HPLC.
Store at -20°C. Avoid multiple freeze/thaw cycles.
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.
contributes_to insulin-like growth factor I binding; contributes_to opsonin binding; protein binding; protein kinase C alpha binding; contributes_to protein kinase C binding; receptor activity; transforming growth factor beta binding;