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Recombinant Chimeric (mouse/human) Antibody Fab Fragment is directed against Human 5AC, expressed in Chinese Hamster Ovary cells(CHO)
Fab Fragment based on Chimeric (mouse/human) IgG1 - kappa
M1 mucin preparation from the fluid of an ovarian mucinous cyst.
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Predicted N terminal
H chain: QVQLKES; L Chain: QVVLTQS
Purity >95% by SDS-PAGE.
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.