Anti-PDGFRA Antibody Fab

Cat

MOM-18192-F(E)

Product Overview

Recombinant Human Antibody Fab Fragment is bind to Human PDGF-R alpha, expressed in Chinese Hamster Ovary cells(CHO)

Target

PDGF-R alpha

Type

Fab Fragment based on Human IgG1 - kappa

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Predicted N terminal

H chain: QLQLQES; L Chain: EIVLTQS

Purity

>95.0% as determined by analysis by SDS-PAGE.

Storage

At -20°C for one year.

Antigen Description

Receptor that binds specifically to PDGFB and PDGFD and has a tyrosine-protein kinase activity. Phosphorylates Tyr residues at the C-terminus of PTPN11 creating a binding site for the SH2 domain of GRB2.

Function

ATP binding; nucleotide binding; phosphatidylinositol 3-kinase binding; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor binding; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein homodimerization activity; protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor binding; vascular endothelial growth factor-activated receptor activity;

Gene ID

5156

Synonyms

PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795;

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