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The details of the immunogen for this antibody are not available.
Tested positive against native human antigen.
Store at -20°C. Avoid multiple freeze/thaw cycles.
Zinc finger protein RFP is a protein that in humans is encoded by the TRIM27 gene.
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
DNA binding; ligase activity; metal ion binding; nucleic acid binding; protein binding; transmembrane receptor protein tyrosine kinase activity; ubiquitin-protein transferase activity; ubiquitin-protein transferase activity; zinc ion binding.