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Recombinant Human Antibody binds selectively to Human Rhesus factor, expressed in Chinese Hamster Ovary cells(CHO)
Tissue / cell preparation (Human) - erythrocytes.
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
Immunoglobulin G1, anti-(human Rh(D) antigen) (human monoclonal clone 190/31 ?1-chain), disulfide with human monoclonal clone 190/31 k-chain, dimer
Purity >95% by SDS-PAGE.
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.