Recombinant Anti-S-layer protein Single Domain Antibody

Cat

NAB-L113

Product Overview

Single Domain Antibody to human S-layer protein.

Target

S-layer protein

Type

llama Single Domain Antibody

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

E.coli

Specificity

Tested positive against native human antigen.

Storage

Store at -20°C. Avoid multiple freeze/thaw cycles.

Introduction

An S-layer (surface layer) is a part of the cell envelope commonly found in bacteria, as well as among archaea. It consists of a monomolecular layer composed of identical proteins or glycoproteins. This structure is built via self-assembly and encloses th

Antigen Description

An S-layer (surface layer) is a part of the cell envelope commonly found in bacteria, as well as among archaea. It consists of a monomolecular layer composed of identical proteins or glycoproteins. This structure is built via self-assembly and encloses the whole cell surface. Thus, the S-layer protein can represent up to 10–15% of the whole protein content of a cell. S-layer proteins are poorly conserved or not conserved at all, and can differ markedly even between related species. Depending on species, the S-layers have a thickness between 5 and 25 nm and possess identical pores with 2–8 nm in diameter. S-layers exhibit either an oblique (p1, p2), square (p4) or hexagonal (p3, p6) lattice symmetry. Depending on the lattice symmetry, the S-layer is composed of one (P1), two (P2), three (P3), four (P4), or six (P6) identical protein subunits, respectively. The center-to-center spacings (or unit cell dimensions) between these subunits range between 2.5 and 35 nm.

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