Anti-SDC1 Antibody Fab

Cat

MOM-18197-F(E)

Product Overview

Recombinant Chimeric (mouse/human) Antibody Fab Fragment is directed against Human SDC1, expressed in Chinese Hamster Ovary cells(CHO)

Target

SDC1

Type

Fab Fragment based on Chimeric (mouse/human) IgG4 - kappa

Immunogen

U266 cell line

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

At -20°C for one year.

Antigen Description

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Function

cytoskeletal protein binding; glycoprotein binding; lipoprotein lipase activity; protein C-terminus binding; protein binding;

Gene ID

6382

Synonyms

SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor;

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