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Anti-SDC1 Antibody Fab (MOM-18197-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human SDC1 Antibody Fab Fragment MOM-18197-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Chimeric (mouse/human) Antibody Fab Fragment is directed against Human SDC1, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • SDC1
  • Type
  • Fab Fragment based on Chimeric (mouse/human) IgG4 - kappa
  • Immunogen
  • U266 cell line
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
  • Function
  • cytoskeletal protein binding; glycoprotein binding; lipoprotein lipase activity; protein C-terminus binding; protein binding;
  • Synonyms
  • SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor;

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