Anti-SDC1 Antibody scFv

Cat

MOM-18197-S(P)

Product Overview

Recombinant Chimeric (mouse/human) Antibody scFv Fragment is bind to Human SDC1, expressed in E. coli

Target

SDC1

Type

scFv Fragment from Chimeric (mouse/human) IgG4 - kappa

Immunogen

U266 cell line

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in ELISA, WB, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0% as determined by analysis by RP-HPLC.

Storage

Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Antigen Description

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Function

cytoskeletal protein binding; glycoprotein binding; lipoprotein lipase activity; protein C-terminus binding; protein binding;

Gene ID

6382

Synonyms

SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor;

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