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Anti-SDC1 Antibody (MOM-18197)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human SDC1 Antibody MOM-18197 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Chimeric (mouse/human) Antibody is specific to Human SDC1, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • SDC1
  • Type
  • Chimeric (mouse/human) IgG4 - kappa
  • Immunogen
  • U266 cell line
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Protein Construction
  • Immunoglobulin G4-kappa, anti-[Homo sapiens SDC1 (syndecan-1, CD138)], chimeric monoclonal antibody conjugated to maytansinoid DM4
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
  • Function
  • cytoskeletal protein binding; glycoprotein binding; lipoprotein lipase activity; protein C-terminus binding; protein binding;
  • Synonyms
  • SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor;

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