Close

Anti-SOST Antibody (MOM-18115)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human SOST Antibody MOM-18115 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) Antibody is specific to Human SOST, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • SOST
  • Type
  • Humanized (from mouse) IgG4 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Protein Construction
  • Immunoglobulin G4, anti-(human sclerostin) (human-Mus musculus monoclonal heavy chain), disulfide with human-Mus musculus monoclonal Kappa-chain, dimer
  • Predicted N terminal
  • H chain: QVQLVQS; L Chain: DIQMTQS
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antaggedonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
  • Function
  • heparin binding; protein binding; transcription factor binding;
  • Synonyms
  • SOST; sclerostin; sclerosteosis; VBCH;

Related Products

Online Inquiry

Verification code
Click image to refresh the verification code.

CONTACT US

45-1 Ramsey Road, Shirley, NY 11967, USA
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us