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Anti-TGFB1 Antibody Fab (CAT#: MOM-18140-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TGFB1 Antibody Fab Fragment MOM-18140-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human Antibody Fab Fragment is directed against Human TGF-beta, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • TGF-beta
  • Type
  • Fab Fragment based on Human IgG4 - kappa
  • Immunogen
  • A synthetic peptide (17 aa) derived from C terminal human TGF beta 3 protein.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Predicted N terminal
  • H chain: QVQLVQS ; L Chain: ETVLTQS
  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
  • Function
  • enzyme binding; eukaryotic cell surface binding; growth factor activity; protein N-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding;
  • Synonyms
  • TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide; LAP; DPD1; TGFB;

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