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Recombinant Human Antibody Fab Fragment is directed against Human TGF-beta, expressed in Chinese Hamster Ovary cells(CHO)
Fab Fragment based on Human IgG4 - kappa
A synthetic peptide (17 aa) derived from C terminal human TGF beta 3 protein.
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Predicted N terminal
H chain: QVQLVQS ; L Chain: ETVLTQS
Purity >95% by SDS-PAGE.
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
enzyme binding; eukaryotic cell surface binding; growth factor activity; protein N-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding;