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Recombinant Human Antibody scFv Fragment is bind to Human DR5, expressed in E. coli
scFv Fragment from Human IgG1 - lambda
The details of the immunogen for this antibody are not available.
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Purity >95% by SDS-PAGE.
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
TRAIL binding; protein binding; receptor activity;