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Recombinant Humanized Antibody Fab Fragment is bind to Human Von Willebrand Factor, expressed in Chinese Hamster Ovary cells(CHO)
Von Willebrand Factor
Fab Fragment based on Humanized VH - VH
Full length protein (Human)
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
Predicted N terminal
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
chaperone binding; collagen binding; glycoprotein binding; immunoglobulin binding; integrin binding; protease binding; protease binding; protein N-terminus binding; protein binding; protein homodimerization activity;