Anti-alk Antibody scFv

Cat

MOM-18269-S(P)

Product Overview

Recombinant Mouse Antibody scFv Fragment is bind to Human ALK, expressed in E. coli

Target

ALK

Type

scFv

Immunogen

Prokaryotic recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of NPM-ALK transcript (419-520 aa).

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in ELISA, WB, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage

At -20°C for one year.

Antigen Description

Orphan receptor with a tyrosine-protein kinase activity. Appears to play an important role in the normal development and function of the nervous system. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif.

Function

ATP binding; NF-kappaB-inducing kinase activity; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity;

Gene ID

238

Synonyms

ALK; anaplastic lymphoma receptor tyrosine kinase; anaplastic lymphoma kinase (Ki 1); ALK tyrosine kinase receptor; CD246; CD246 antigen; mutant anaplastic lymphoma kinase; NBLST3

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