Anti-apoe Antibody Fab

Cat

MOM-18278-F(E)

Product Overview

Recombinant Mouse Antibody Fab Fragment is directed against Human APOE, expressed in Chinese Hamster Ovary cells(CHO)

Target

APOE

Type

Fab

Immunogen

Synthetic peptide spanning the polymorphic amino acid position 158 of ApoE.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage

Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Antigen Description

Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.

Function

antioxidant activity; beta-amyloid binding; cholesterol transporter activity; heparin binding; identical protein binding; lipid binding; lipid transporter activity; lipoprotein particle binding; low-density lipoprotein particle receptor binding; low-density lipoprotein particle receptor binding; metal chelating activity; phosphatidylcholine-sterol O-acyltransferase activator activity; phospholipid binding; protein binding; protein heterodimerization activity; protein homodimerization activity; tau protein binding; very-low-density lipoprotein particle receptor binding; very-low-density lipoprotein particle receptor binding;

Gene ID

348

Synonyms

APOE; apolipoprotein E; AD2, Alzheimer disease 2 (APOE*E4 associated, late onset); apo-E; apolipoprotein E3; AD2; LPG; LDLCQ5; MGC1571

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