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Anti-cd22 Antibody (MOM-18047)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human cd22 Antibody MOM-18047 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody is against Human CD22, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • CD22
  • Type
  • Mouse IgG2a
  • Immunogen
  • A combination of recombinant human CD22 extracellular 25 domain and CHO ceIls engineered to express full-length human CD22 on the ceIl surface
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, IHC and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Predicted N terminal
  • H chain: EVQLVQS; L Chain: EIVLTQS
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling.
  • Function
  • Carbohydrate binding; Protein binding
  • Synonyms
  • SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; BLCAM; Leu14; Siglec-2

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