Anti-cxcr5 Antibody

Cat

MOM-18338

Product Overview

Recombinant Mouse Antibody is specific to Human CXCR5, expressed in Chinese Hamster Ovary cells(CHO)

Target

CXCR5

Type

IgG

Immunogen

Recombinant full length Human CXCR5 protein

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0% as determined by analysis by RP-HPLC.

Storage

Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

Antigen Description

The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.

Function

C-X-C chemokine receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity;

Gene ID

643

Synonyms

CXCR5; chemokine (C-X-C motif) receptor 5; BLR1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C X C motif) receptor 5) , Burkitt lymphoma receptor 1, GTP binding protein; C-X-C chemokine receptor type 5; CD185; MDR15; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); BLR1; MGC117347

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