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Recombinant Mouse Antibody scFv Fragment is directed against Human GNRHR, expressed in E. coli
Synthetic peptide: MANSASPEQNQHCSAINNSIPLMQGNLPY conjugated to BSA, corresponding to N terminal amino acids 1-29 of Human GnRHRMANSASPEQNQHCSAINNSIPLMQGNLPY
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Tested positive against native antigen.
>95.0% as determined by analysis by SDS-PAGE.
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Gonadotropin Releasing Hormone (GnRH) is down-regulated by hCG and believed to be an autocrine factor that regulates the ovary. The Gonadotropin Releasing Hormone Receptor (GnRHR) is synthesized in the pituitary gland. Activin A has been shown to stimulate the synthesis of GnRHR, illustrating a possible mechanism for the modulation of gonadotropin responsiveness to GnRH.