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Anti-il23r Antibody Fab (MOM-18396-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human il23r Antibody Fab Fragment MOM-18396-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is specific to Human IL23R, expressed in E. coli
  • Target
  • IL23R
  • Type
  • Fab
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
  • Function
  • contributes_to interleukin-12 receptor binding; contributes_to interleukin-23 binding; contributes_to interleukin-23 receptor activity; receptor activity;
  • Synonyms
  • IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor

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