Anti-irak4 Antibody scFv

Cat

MOM-18416-S(P)

Product Overview

Recombinant Mouse Antibody scFv Fragment specifically binds to Human IRAK4, expressed in E. coli

Target

IRAK4

Type

scFv

Immunogen

Recombinant fragment, corresponding to amino acids 21-198 of Human IRAK4

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in ELISA, WB, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Antigen Description

Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.

Function

ATP binding; interleukin-1 receptor binding; magnesium ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity;

Gene ID

51135

Synonyms

IRAK4; interleukin-1 receptor-associated kinase 4; NY REN 64; renal carcinoma antigen NY-REN-64; IPD1; REN64; IRAK-4; NY-REN-64

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