Anti-madcam1 Antibody Fab

Cat

MOM-18588-F(E)

Product Overview

Recombinant Mouse Antibody Fab Fragment is directed against Human MADCAM1, expressed in Chinese Hamster Ovary cells(CHO)

Target

MADCAM1

Type

Fab

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95%, by SDS-PAGE with silver staining, under reducing conditions.

Storage

4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Antigen Description

Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Gene ID

8174

Synonyms

MADCAM1; mucosal vascular addressin cell adhesion molecule 1; mucosal addressin cell adhesion molecule 1; MACAM1; MAdCAM-1; hMAdCAM-1; mucosal addressin cell adhesion molecule-1;

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