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Recombinant Mouse Antibody scFv Fragment specifically binds to Human MCM6, expressed in E. coli
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Tested positive against native antigen.
Purity >95% by SDS-PAGE.
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for "once per cell cycle" DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
ATP binding; contributes_to ATP-dependent DNA helicase activity; DNA binding; hydrolase activity; identical protein binding; nucleotide binding; protein binding; single-stranded DNA binding;