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Recombinant Mouse Antibody Fab Fragment is bind to Human MMP9, expressed in Chinese Hamster Ovary cells(CHO)
Synthetic peptide: LFSGRRLWRFDVKAQMVDP, corresponding to amino acids 626-644 of Human MMP9LFSGRRLWRFDVKAQMVDP
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Store at -20°C. Avoid multiple freeze/thaw cycles.
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly--Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter Fragment and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
collagen binding; fibronectin binding; metal ion binding; metalloendopeptidase activity; peptidase activity; protein binding; protein complex binding; zinc ion binding;