Anti-muc1 Antibody Fab

DESCRIPTION	CATALOG #	SIZE	PRICE
Recombinant Anti-Human muc1 Antibody Fab Fragment	MOM-18065-F(E)	1mg	Please Inquiry

Product Detail

Product Overview: Recombinant Mouse Antibody Fab Fragment is bind to Human MUC1, expressed in Chinese Hamster Ovary cells(CHO)

Immunogen: The details of the immunogen for this antibody are not available.

Applications: Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Storage: 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Background

Antigen Description: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding; p53 binding; protein binding; transcription cofactor activity

Synonyms: EMA; PEM; PUM; KL-6; MAM6; PEMT; CD227; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC; Episialin; DF3; H23; Krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen;Breast carcinoma associated antigen DF3; CA15.3; CD227 antigen; Epithelial membrane antigen; Epithelial mucin tandem repeat sequence; H23 antigen; H23AG; KL 6; Krebs von den Lungen-6; Mucin 1 precursor; Mucin-1 subunit beta; Peanut reactive urinary mucin