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Recombinant Mouse Antibody is specific to Human MYH14, expressed in Chinese Hamster Ovary cells(CHO)
Suitable for use in Neut, ELISA, ICC and most other immunological methods.
Tested positive against native antigen.
>95.0% as determined by analysis by RP-HPLC.
Store at -20°C. Avoid multiple freeze/thaw cycles.
The Myh14 gene codes for the heavy chain of non-muscle myosin IIC (NMMHC-IIC). Ablation of NMMHC-IIC in mice results in lethality by E6.5 with defects in cell-cell adhesion and a failure to produce a competent visceral endoderm. Defects in Myh14 are also the cause of non-syndromic sensorineural deafness autosomal dominant type 4 (DFNA4).
ATP binding; actin filament binding; actin-dependent ATPase activity; calmodulin binding; microfilament motor activity; nucleotide binding;